Perfect medicine for white spots Melanogrit
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Dr. Anurag Varshney
Vice President- Patanjali Research Institute
Melanin is a very important pigment for our body which not only gives the skin its color but also protects it from ultraviolet rays of the sun. Amount of melanin in everyone's body it varies, it is found in abundance in the people of countries living around the equator, on the other hand, as we move towards the polar regions, its quantity decreases. Melanocytes are the cells that produce melanin. Like an onion, its skin also has many layers.
The amount of melanin varies in everyone's body, it is found in abundance in people of countries living around the equator, on the other hand, as we move towards the polar region, this amount decreases. |
There are three layers of skin, the uppermost layer is called epidermis, the middle layer is called dermis and the lowest layer is called hypodermis. Melanin is formed at the junction of the upper layer of skin, the epidermis, and the middle layer, the dermis. Keratinocytes and melanocytes are normally found in the epidermis. Melanocytes are cells that contain melanosomes that make melanin. This melanin spreads throughout the body through keratinocyte cells which protect our body from the ultraviolet rays of the sun.
In common language, vitiligo and leucoderma are considered to be the same disease, but leucoderma is a disease caused by an accident whereas vitiligo is a type of auto immune disease |
Vitiligo, leucoderma, white spots, and leprosy are seen as a physical disease as well as a stigma in the society.
Vitiligo, leucoderma and white spots are the only diseases
Vitiligo, leucoderma, white spots or spots, and leprosy are a physical disease as well as a stigma in the society in which the patient develops white patches on his hands and legs. According to a report, one out of every hundred people has vitiligo. In this disease, small white spots or big white spots appear on the person's body. In this disease, melanocyte cells in the body die and melanin production stops. In some patients, the skin becomes red and rough along with swelling in the hands.
The formation of melanin in the body is a complex process, in which the formation of L-dopa, which is a type of amino acid, by a type of enzyme tyrosinase determines how many types of melanin synthesis will take place in the body, while Microphthalmia Associated Transcription Factor (MITF) determine the level of melanin in the body.
Difference between vitiligo and leucoderma
Often in common parlance, vitiligo and leucoderma are considered to be the same disease, but leucoderma is a disease caused by an accident, whereas vitiligo is a type of disease.
In common parlance, vitiligo and leucoderma are considered to be the same disease, but leucoderma is a disease caused by an accident whereas vitiligo is a type of auto immune disease. |
In common language, vitiligo and leucoderma are considered to be the same disease, but leucoderma is a disease caused by an accident whereas vitiligo is a type of auto immune disease is an auto immune disease. In leucoderma, some kind of injury to the skin is necessary, on the other hand, vitiligo can be caused by hormonal imbalance, allergy caused by deodorant, perfume or any chemical substance, frequent jaundice or typhoid, any more sensitive event, or It can also be caused by prolonged use of antibiotic medicines. At the same time, sometimes the immune system itself starts destroying melanocytes unknowingly. The treatment of both is almost the same because in both, pigmentation and immunity enhancing medicines are given, hence it becomes even more difficult to tell the difference.
After giving melanogrit, the fiber-like structures present inside the cells, called dendrites, also expanded. |
Melanogrit is made from purified herbs like Bakuchi, Khadir, Manjistha, Amaltas, Ras Manikya, Tamra Bhasma etc.
Are steroids the solution?
The treatment given in modern medical systems is mostly in the form of steroids which are given to increase the immunity. These medicines also have a lot of side effects on the body. Many times due to this, skin cells start dying, or more hair starts growing on the skin, sometimes the complexion of the skin gets fine but it gets wrinkled and sometimes there is a burning sensation when exposed to sunlight. .
Melanogrit is the first herbo mineral medicine made according to the ancient Indian medical system
Melanogrit made from herbs like Shodhit Bakuchi, Khadir, Manjishtha, Amaltas, Ras Manikya, Tamra Bhasma etc. is the first herbo mineral medicine of its kind, which has been made in accordance with the ancient Indian medical system. It is not only helpful in curing skin diseases like vitiligo and leucoderma, but protects in reducing the social and economic losses caused by these diseases.
After giving melanogrit, the fiber-like structures present inside the cells, called dendrites, also expanded. |
To authenticate the herbs of this medicine made on the basis of ancient texts of Ayurveda, first of all through high performance liquid chromatography technique it was seen which are the signature phytometabolites which are directly helpful in curing melanin and They were standardized. The first objective of this process was to discover those elements which are beneficial in these diseases according to Ayurvedic texts, secondly it was also necessary to ensure that whatever Ayurvedic medicine is being manufactured, all those elements are present in the right quantity. Subsequently, tissues were prepared in the laboratory to test the cells and it was observed that this medicine was not causing any harm to the skin. Even with a Melanogrit dose of 100 micrograms/ml, it was observed that there was no harm to these cells. After that, it has also been observed that after giving melanogrit, the fiber like structures present in these cells which are called dendrites are also expanding. These dendrites decide to what extent they can maintain their connectivity, so that signals from one cell to another melanin can be delivered to the cell.
Melanogrit not only cures diseases physically but also eliminates social stigma. |
This process of melanin production takes place through three different proteins or enzymes. Gene expression of those enzymes an attempt was also made to observe, then it was found that during vitiligo and leucoderma, when the level of expression of these genes is low, it can be corrected in a dose dependent manner with the help of Melanogrit.
Cellular tyrosinase activity can also be increased by the use of melanogrit. |
After this, the authenticity of Melanogrit was confirmed by another research, for this it was found through Alpha MSH (Alpha-Melanin Stimulating Hormone), which is a type of hormone and Ayurvedic herbal medicine Melanogrit that if healthy cells are first If this hormone is induced then the color of the cells becomes black and then if the amount of this hormone is further reduced then they become transparent.
But with the use of melanogrit, they can be restored to the same shape and color as healthy cells.
After that, an attempt was made to know its mode of action, research on tyrosinase, an enzyme that controls the level of L-dopa, it was found that the use of melanogrit can also increase cellular tyrosinase activity, which is Certifies that enzyme activity inside skin cells has increased. In another research it was proved that the use of melanogrit
MITF, a large transcription cell, can also be controlled. In this research it was found that its level increases with the use of Melanogrit in a dose dependent manner. Apart from this, by doing research on a special protein ERK which is a type of kinase, it was found that its phosphorylation can also be balanced by the use of Melanogrit.
Melanogrit is not only beneficial in treating white spots caused by injuries like leucoderma but is also a suitable Ayurvedic medicine to eradicate vitiligo caused due to hormonal imbalance and medicines. This Ayurvedic medicine not only cures these diseases physically but also eliminates social stigma.
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15 Jan 2025 12:10:16
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